Mediterranean cruise holidays
The Mediterranean is famed for its agreeable climate, compelling coastlines and delicious cuisines; not to mention its world-renowned art and architecture. A Mediterranean cruise holiday offers something special to discover at every port.
Reasons to visit the Mediterranean with P&O Cruises
Amazing architecture
You’re spoiled for choice on a cruise across the Mediterranean. With ornate archways of palaces and cathedrals, red roofs and whitewashed walls of seaside villas, the architecture of the region delights at every turn.
Mediterranean delights
Dining in the Med is a daily dream for your taste buds. Each city boasts its own specialities and flavours so why not explore a local food market, join a cookery class or take a food tour to get a taste for the local cuisine?
Stunning seashores
Long sandy stretches, turquoise waters and crystal-clear pools – the beaches of the Med, blessed with warmer temperatures and sunny skies, are eternally appealing. Whatever you’re mood, you’ll find beautiful beaches are typically just a stone’s throw away from each port.
Explore our Mediterranean cruise destinations
Your journey to a Mediterranean haven

Sail from Southampton
Start your holiday the minute you step on board. Stress-free travel, no luggage weight limits, and all the exciting on-board activities, from the moment you arrive at Southampton port. You're not travelling by air, you're travelling by hot tub.

Seamless skies to seas
On a Mediterranean fly-cruise,you'll be sipping a cocktail and embarking on an unforgettable cruise through the azure waters in no time. Your flights are all taken care of in your holiday price, and we're also including complimentary transfers between Malta International Airport and your P&O Cruises ship in Valletta. Still have questions? Head to our Help Hub.
Featured Mediterranean fly cruises
Featured Mediterranean cruises
Brand new Summer 2028 holidays available now
Inspired Mediterranean itineraries
Shore experiences
Explore the Med like never before with our unforgettable shore experiences. Climb to the Acropolis and marvel at the Parthenon in Athens, or kayak along the stunning Adriatic coast in Croatia. For food lovers, prepare your palate to explore the rich local cuisine.
Explore the Med on your favourite ship
Arvia
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